Clotrimazole

Clotrimazole has activity against dermatophytes and yeasts;

it may be useful for localized lesions associated with Malassezia.

It is not very effective in treating dermatophytosis in cats.

Clotrimazole inhibits the biosynthesis of ergosterol, a component of fungal cell membranes leading to increased membrane permeability and probable disruption of membrane enzyme systems.